Director, Translational Sciences
New
United StatesFull-TimeDirector
Salary171,600 - 214,500 USD per year
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Job Details
- Experience
- PhD or equivalent degree in Immunology, Biology, Pharmacology, or a related scientific field with 8+ years of post-graduate industry or translational research experience; alternatively, an MS degree with 12+ years of directly relevant experience.
- Required Skills
- Project ManagementStakeholder management
Requirements
- PhD or equivalent degree in Immunology, Biology, Pharmacology, or a related scientific field with 8+ years of post-graduate industry or translational research experience; alternatively, an MS degree with 12+ years of directly relevant experience.
- Deep expertise in immuno-oncology, immune functional assays, mechanistic biology, and translational research methodologies.
- Proven experience leading externalized R&D programs through CROs and academic collaborations, including governance, experimental design, and milestone management.
- Strong understanding of high-dimensional biological data analysis, including technologies such as single-cell sequencing and AI-driven target validation approaches.
- Demonstrated experience in assay development, assay transfer, and ensuring reproducibility and scientific quality standards.
- Excellent project management skills with the ability to manage budgets, timelines, risks, and multiple parallel research initiatives.
- Strong communication and stakeholder management capabilities with the ability to translate complex scientific findings into actionable business recommendations.
- Ability to work effectively in cross-functional and fast-paced research environments with an ownership-driven mindset.
- Expertise in neoantigen biology, antigen presentation validation, or tumor model systems is considered highly desirable.
- Strong leadership and mentoring abilities with a commitment to scientific collaboration and innovation.
Responsibilities
- Lead and oversee external pre-clinical translational research programs through CRO and academic partnerships focused on immuno-oncology therapies.
- Direct functional validation initiatives including immunogenicity studies, mechanism of action investigations, T-cell assays, and biomarker validation.
- Develop experimental strategies, define research frameworks, and manage statements of work, timelines, budgets, and partner performance.
- Drive the validation of AI/ML-derived targets and biomarkers using patient-derived samples and advanced immune functional assays.
- Incorporate high-throughput screening methodologies to validate drug-target interactions and ensure data quality suitable for regulatory and clinical translation.
- Collaborate closely with R&D, Clinical Development, and Regulatory teams to align scientific outputs with program milestones and development objectives.
- Build and maintain a scalable external network across immunology and tumor biology while contributing to long-term internal translational research capability development.
- Deliver clear, data-driven scientific updates and actionable recommendations to leadership and cross-functional stakeholders.
- Mentor scientific staff and external collaborators, fostering a culture of scientific excellence, accountability, and operational rigor.
- Support the evolution of translational research infrastructure through strategic evaluation of internal versus external capabilities.
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