Clinical Trial Manager (CTM)

New

US/RemoteFull-TimeManager

Salary132000 - 178000 USD per year

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Job Details

Experience: 2+ years

Requirements

Hands-on Clinical Research Associate (CRA) experience, including on-site monitoring (not remote-only)
2+ years of experience as a Clinical Trial Manager
Strong understanding of global clinical trial operations and site management
Demonstrated success leading cross-functional, global clinical teams
Solid experience with risk-based monitoring and centralized oversight models
Deep knowledge of ICH-GCP and international regulatory requirements
Strong analytical, critical-thinking, and problem-solving capabilities
Proficiency with clinical trial systems (CTMS, EDC, ePRO, TMF)
Experience in oncology and/or ophthalmology is a strong asset

Responsibilities

Lead end-to-end clinical trial execution, ensuring delivery against timelines, quality standards, and budget
Provide operational oversight of site management and monitoring activities, including on-site and centralized monitoring
Identify, assess, and proactively mitigate clinical and operational risks using a risk-based management approach (RACT)
Serve as the primary escalation point for CRAs, investigative sites, and cross-functional stakeholders
Partner closely with Study Start-Up, Data Management, Biostatistics, Safety, and Patient Recruitment teams to drive milestone achievement
Leverage integrated systems and data (CTMS, EDC, ePRO, TMF, dashboards) to monitor performance, trends, and risk indicators
Ensure ongoing inspection readiness and compliance with ICH-GCP, SOPs, and global regulatory requirements
Lead study-specific training and foster alignment across the clinical trial team
Review metrics and operational data to anticipate challenges and implement timely solutions
Mentor and support CRAs, contributing to a culture of accountability, continuous improvement, and collaboration

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132000 - 178000 USD per year

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