Senior Director, Global Commercial Development

New
R
Revolution MedicinesOncology pharmaceuticals
Remote (United States)Full-TimeDirector
Salary232,000 - 290,000 USD per year
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Job Details

Experience
Bachelor’s degree with at least 15 years, or advanced degree with at least 8 years, of progressive commercial experience in a biotechnology and/or pharmaceutical company
Required Skills
Cross-functional Team Leadership

Requirements

  • Hold a bachelor’s degree with at least 15 years, or an advanced degree with at least 8 years, of progressive commercial experience in biotechnology or pharmaceuticals.
  • Bring strategic marketing experience; sales experience is preferred.
  • Have proven success developing global oncology commercial strategies across products, indications, or stages of disease.
  • Demonstrate experience influencing complex cross-functional product teams.
  • Be able to develop patient and revenue forecasts, interpret market and clinical insights, and evaluate strategic trade-offs.
  • Bring strong clinical and scientific acumen, including the ability to translate clinical evidence, trial design, and oncology treatment pathways into commercial implications.
  • Demonstrate leadership and the ability to build teams and partnerships and influence without direct authority.
  • Have strong organizational and prioritization skills and deliver strategic work under evolving timelines.
  • Have executive communication, presentation, and external stakeholder engagement skills.
  • Be available for up to 40% travel.
  • Preferred: experience in pancreatic or other gastrointestinal cancers, including first-line metastatic and earlier-stage settings.
  • Preferred: experience with precision oncology, KRAS/RAS-targeted medicines, molecular testing, or biomarker-defined populations.
  • Preferred: experience with oncology launches, indication expansion, lifecycle management, and global or regional commercial organizations.

Responsibilities

  • Lead global commercial development across pancreatic cancer therapeutic settings and connect indication strategies to portfolio value.
  • Evaluate clinical and commercial opportunities, unmet need, competitive differentiation, treatment sequencing, and investment trade-offs.
  • Develop commercial hypotheses for first-line, locally advanced, surgical/perioperative, and adjuvant treatment settings.
  • Partner with product teams on daraxonrasib and zoldonrasib positioning, biomarker-defined populations, and potential combination approaches.
  • Develop global epidemiology, treatment-flow, patient-segmentation, revenue, and sensitivity models.
  • Collaborate with Clinical Development, Medical Affairs, HEOR, and Market Access on target populations, endpoints, standards of care, and evidence needs.
  • Work with Precision Medicine and Diagnostics on RAS/KRAS testing, patient identification, laboratory and referral workflows, and access.
  • Coordinate with regional affiliates, global brand teams, and existing indication teams on strategy and launch readiness.
  • Develop commercialization frameworks, value propositions, brand positioning, affiliate readiness, access assumptions, and launch scenarios.
  • Monitor scientific milestones, competing programs, diagnostic adoption, and treatment patterns; guide cross-functional teams and communicate recommendations to senior leaders.
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232,000 - 290,000 USD per year
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