Senior Medical Science Liaison - Gene Therapy US Medical Affairs

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Orchard TherapeuticsGene therapy
Remote, Eastern Territory USFull-TimeSenior
Salary190,000 - 240,000 USD per year
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Job Details

Languages
Fluency in both spoken and written English
Experience
Minimum of 5 years of experience in a scientific, clinical or MSL role within the biotech or pharmaceutical industry
Required Skills
Cross-functional Team Leadership

Requirements

  • Advanced scientific or healthcare degree (PhD, PharmD, MD, NP, DVM, CGC, or similar preferred); RN, MS, or similar with substantial experience considered.
  • Minimum of 5 years of experience in a scientific, clinical, or MSL role in the biotech or pharmaceutical industry.
  • Extensive experience as an MSL supporting post-approval commercial products in the field.
  • Experience in hematopoietic stem cell transplantation, gene therapy, or neurology/genetics; neurometabolic genetics preferred.
  • Ability to lead, coach, and mentor colleagues without direct reporting authority.
  • Track record of building trusted relationships with healthcare provider thought leaders and clinical care teams.
  • Understanding of US government and industry guidelines, regulations, and laws for compliant scientific and clinical information exchange.
  • Experience developing and delivering scientific educational materials and programs for multispecialty audiences.
  • Strong knowledge of and established network with healthcare providers and industry experts.
  • Fluency in spoken and written English.
  • Valid US driver's license and clean driving record.
  • Ability to travel frequently (75%), often overnight.

Responsibilities

  • Build and maintain collaborative partnerships with healthcare providers, key opinion leaders, and academic institutions.
  • Provide audience-appropriate scientific and medical information about Orchard's programs.
  • Maintain training records and deliver training updates for personnel at assigned Qualified Treatment Centers.
  • Develop territory profiles covering Centers of Excellence, expertise, newborn screening approaches, leaders, and market access pathways.
  • Gather field insights on data, therapeutic areas, and competitive intelligence to inform company strategies and evidence generation plans.
  • Review and oversee Investigator-Sponsored Trial and Early Access Program requests through internal review and follow-up.
  • Build partnerships across Medical Affairs, Patient Advocacy, Public Affairs, Clinical Development, Clinical Operations, Technical Operations, Market Access, and Commercial.
  • Develop strategic field medical initiatives and resources for stakeholder groups, disease states, and technology.
  • Lead cross-functional projects while maintaining geographic responsibilities.
  • Mentor and coach new or junior MSLs, supporting onboarding, training, and field excellence.
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190,000 - 240,000 USD per year
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