Principal Scientist, Pharmacometrics

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Requirements:

• Ph.D. in pharmaceutical sciences, pharmacology, pharmacometrics, pharmacokinetics, or related discipline or Pharm.D. or M.D. with relevant experience.
• 4+ years’ experience with background in the application of mathematical, pharmacokinetics, and statistical methods within pharma/biotech industries or drug development.
• Experience using Phoenix WinNonlin, R, NONMEM, MATLAB, or other pharmacokinetic and modeling software.
• Strong mathematical model development and analytical skills.
• Proficient documentation and organizational skills, as well as proven ability to be self-motivated and able to work independently.
• Excellent communication and presentation skills to efficiently relay information to project teams and other key stakeholders.
• Ability to travel approximately 15% of the time, as determined by the needs of the business.

Responsibilities:

• Use modeling approaches to advance clinical and translational research at Entrada Therapeutics.
• Lead cross-functional teams with scientific acumen to develop and execute. pharmacometrics for programs across all phases of drug development.
• Support the development of diverse modeling strategies and execution, in collaboration with the Head of Clinical Pharmacology, to bring value to the Entrada portfolio.
• Work collaboratively with functional partners, including Clinical Development, Biostatistics, Non-Clinical Product Development, Clinical Operations, and Regulatory to deliver on both project team and corporate objectives.
• Author regulatory documents including analysis plans, study reports, population PK reports, exposure-response analyses reports and other similar documents.
• Monitor work with CROs and other external vendors to ensure compliance with agreed protocols, quality standards, and timelines.